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  • Writer's pictureAlly McClure

Best of BioRankings: 2019

It's been a heck of a year at BioRankings. With 2020 on the horizon, it's a great time to look back at some of the greatest hits of 2019.


New Publication:

December 2019 saw the publication of our paper, "New statistical method identifies cytokines that distinguish stool microbiomes", in Nature Scientific Reports.

This paper is the culmination of research undertaken with our longtime collaborators at the Jackson Laboratory for Genomic Medicine and introduces DM-RPart, a non-parametric regression model for microbiome data.


New Addition:

We welcomed Mr. Carlos Gonzalez to the BioRankings team. Carlos worked with most of us at Washington University School of Medicine, and we're thrilled to have him join our venture as a staff statistician.

Before arriving at BioRankings, Carlos used his SAS skills to help move data for millions of clients from one system to another for a financial institution, and prior to that he was leading a team of data managers to complete the processing of hundreds of clinical trials. His fluency in Spanish is an asset to the company.

Outside of work Carlos can be seen playing Pokemon Go! and rooting for the Atlanta Falcons.


Continuing Research:

This year saw the completion of our Phase I NIH SBIR, "Object Oriented Data Analysis for Untargeted Metabolomics" to create methods and software for automatic, unbiased peak detection in untargeted metabolomics data. The Phase II grant for $1.6 million to develop these methods into a researcher-facing software has received a fundable score.


We continued our research into statistical approaches for analysis of combined multi-omics data. As with all BioRankings research, our methods focus on translational research and bringing products to market. Our multi-omics approach, RLQ, was presented at the Symposium on Gut Health in Production of Food Animals 2019 in St. Louis. Video of the presentation, courtesy of Engormix, can be found HERE.


Our approaches for Internet-of-Things (IoT) sensor data have continued to develop with the creation of Spoke Analytics to further pursue the technology in medicine.

Spoke Analytics is creating a point-of-care medical device for early detection of adverse events. This technology will be field tested in clinical trials at Washington University School of Medicine starting in 2020.



At BioRankings, we believe in making a difference in our community. 2019 was no different as we partnered with two organizations making an impact in the lives of children and our city. Thank you to The Little Bit Foundation for breaking down barriers to learning, and Angels’ Arms for providing and supporting loving homes for foster children!


Thank you for being a supporter in 2019. Here's to 2020!

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